While analyses xccutane suggested buy accutane pills association between isotretinoin therapy and depression, no causal relationship has been established and further studies are required. In the U. more than 2,000 women have become pregnant while taking the drug between 1982 and 2003, with most pregnancies ending in abortion or miscarriage. Oral isotretinoin is marketed under various trade names, buy accutane usa commonly Accutane (Roche), Amnesteem (Mylan), Claravis (Barr), Decutan (Actavis), Isotane (Pacific Pharmaceuticals), Sotret (Ranbaxy), Oratane (Genepharm Australasia) or Roaccutane (Roche); while topical isotretinoin is most commonly marketed under accufane trade names Isotrex or Isotrexin (Stiefel).
On buy isotretinoin grounds that pregnancies by women taking the drug had been underreported by the manufacturer between 1982 and 2000, and that once generic manufacturers entered the market risk buy accutane pills was no bky centralized, the FDA instituted restrictions on prescribing and dispensing the accufane, first with the "System to Manage Accutane Related Teratogenicity" (SMART) in 2000, and subsequently the iPLEDGE program in 2006.
A retrospective cohort study recently found that pregnancy rates were quite high during the period (1 per 30 women per year), but 84 of pregnancies were ended by induced abortion.